SYNTHESIS OF HETEROCYCLES
263
IV.G-6 Naito, T. et al., TL, 35, 2205.
ÌOMe
NHOMe
r~
Bu 3 SnH
-Ύ)
AIBN
^ N
I
Cbz
70%, 1:4 cis:trans
IV.G-7 Einhorn, J., Luche, J.L. et al., CC, 879; see also: Yang, J. et al.,
TL, 35, 3581.
1. NaCNBH
— Ci
3 ,Boc 2 0
k^ ^λ^
+ HCOC0 2 H
2.NaHC0 3
*NH 2
3.LDA(2eq) "
^Γ "C0 2 H
Boc 59%
IV.G-8 Herczegh, P. et al., T, 50, 13671; Iwata, C. et al., TL, 35, 8821;
Kitazume, T. et al., TA, 5, 1029; Bailey, P.D. et al., CC, 2543; Lock, R. and
Waldmann, H. LA, 511.
61-80%, 6:94 to 94:6
263
IV.G-6 Naito, T. et al., TL, 35, 2205.
ÌOMe
NHOMe
r~
Bu 3 SnH
-Ύ)
AIBN
^ N
I
Cbz
70%, 1:4 cis:trans
IV.G-7 Einhorn, J., Luche, J.L. et al., CC, 879; see also: Yang, J. et al.,
TL, 35, 3581.
1. NaCNBH
— Ci
3 ,Boc 2 0
k^ ^λ^
+ HCOC0 2 H
2.NaHC0 3
*NH 2
3.LDA(2eq) "
^Γ "C0 2 H
Boc 59%
IV.G-8 Herczegh, P. et al., T, 50, 13671; Iwata, C. et al., TL, 35, 8821;
Kitazume, T. et al., TA, 5, 1029; Bailey, P.D. et al., CC, 2543; Lock, R. and
Waldmann, H. LA, 511.
61-80%, 6:94 to 94:6