SYNTHESIS OF HETEROCYCLES
237
IV.D-6 Inoue, Y. et al., TL, 35, 5889; see also: Hoye, T.R. et al., TL,
35, 7517.
— V
CO
R N = \
[Pd(MeCN) 2 (PPh 3 ) 2 ](BF 4 ) 2
O H
THF, 50 °C, 1-3 h
' 2 ] ( B F 4 ) 2 /
\ s
12-99% major
IV.D-7 Compain, P., Vatele, J.M. and Gore, J., SL, 943.
^r
S,Me3
Pd(ii)-cuci 2 -o^
CH 3 CN - IN HC1
Xy50-74%
IV.D-8 Lu, X. et al., T, 50, 9067 and TL, 35, 613.
R
PdCl 2 , CuCl 2
propylene oxide
Y
2
HC(OEt) 3
R A V _ < ^
J
Γ
CH 2 C1 2 , MeOH
J.
\
< ^ Ό ' _ w
C0 2 Me
62-80%
IV.D-9 Piva, O., T, 50, 13687.
OEt
TMS-C1 (1 eq)
Nal (1.3 eq)
CH 3 CN, Δ
67-87%
237
IV.D-6 Inoue, Y. et al., TL, 35, 5889; see also: Hoye, T.R. et al., TL,
35, 7517.
— V
CO
R N = \
[Pd(MeCN) 2 (PPh 3 ) 2 ](BF 4 ) 2
O H
THF, 50 °C, 1-3 h
' 2 ] ( B F 4 ) 2 /
\ s
12-99% major
IV.D-7 Compain, P., Vatele, J.M. and Gore, J., SL, 943.
^r
S,Me3
Pd(ii)-cuci 2 -o^
CH 3 CN - IN HC1
Xy50-74%
IV.D-8 Lu, X. et al., T, 50, 9067 and TL, 35, 613.
R
PdCl 2 , CuCl 2
propylene oxide
Y
2
HC(OEt) 3
R A V _ < ^
J
Γ
CH 2 C1 2 , MeOH
J.
\
< ^ Ό ' _ w
C0 2 Me
62-80%
IV.D-9 Piva, O., T, 50, 13687.
OEt
TMS-C1 (1 eq)
Nal (1.3 eq)
CH 3 CN, Δ
67-87%