SYNTHESIS OF HETEROCYCLES
235
IV.C-29 Chuang, C.P. and Wang, S.F., TL, 35, 1283.
CH 2 (C0 2 Me) 2
Mn(OAc) 3
AcOH
80 °C
42-83%
IV.C-30 Lowe, J.A. Ill et al., JMC, 37, 3789.
^
A
PPA
►
DCE
90 °C
NOH
0 2 Me
C0 2 Me
73-80%
IV.D
Lactones
IV.D-1 Miyano, S. et al, CC, 2281 and JCS(Pl), 1549.
R ^ H O + CH 2 =C=0
R 3 A1
—r T ?
S O 2 R
2
I—L
Plw .NH
^R
1
Ρ1Τ*Ι)ΪΗ
S0 2 R
z
11-94%
0-74% ee
IV.D-2 Vederas, J.C. et al., JOC, 59, 3642.
OH
^ ^ ^ γ ^
BrC 6 H 4 S0 2 Cl / pyr
Jv
*
H^
v SAr'
O
24-41%
H ^ ^ S A r '
235
IV.C-29 Chuang, C.P. and Wang, S.F., TL, 35, 1283.
CH 2 (C0 2 Me) 2
Mn(OAc) 3
AcOH
80 °C
42-83%
IV.C-30 Lowe, J.A. Ill et al., JMC, 37, 3789.
^
A
PPA
►
DCE
90 °C
NOH
0 2 Me
C0 2 Me
73-80%
IV.D
Lactones
IV.D-1 Miyano, S. et al, CC, 2281 and JCS(Pl), 1549.
R ^ H O + CH 2 =C=0
R 3 A1
—r T ?
S O 2 R
2
I—L
Plw .NH
^R
1
Ρ1Τ*Ι)ΪΗ
S0 2 R
z
11-94%
0-74% ee
IV.D-2 Vederas, J.C. et al., JOC, 59, 3642.
OH
^ ^ ^ γ ^
BrC 6 H 4 S0 2 Cl / pyr
Jv
*
H^
v SAr'
O
24-41%
H ^ ^ S A r '