REDUCTIONS
IILA-10 Kaptein, B. et al., TL, 35, 1776.
201
R
R*
H 2 N
> O N H 2
O
Na, «PrOH, reflux
R
R'
H 2 N
X^OH
40-99 %
III.A-11 Lemaire, M. et al., CC, 1417; Burk, M.J. et al., TL, 35, 4963;
Takaya, H. et al., JOM, 484, 191; Brunet, J.J. et al., TL, 35, 8801.
O
Λ
Ph
Me
[Rh(C 6 Hio)CI] 2
KOH, propan-2-ol
chiral diamine
OH
Λ.
Ph'
Me
28-55 % e.e. (R)
or
59-60 % e.e. (S)
III.A-12 Singaram, B. et al., JOC, 59, 6378 and TL, 35, 5201; Brussee, J.
et al., TA, 5, 377.
Aminoborohydrides. 4. The Synthesis and Characterization of
Lithium Aminoborohydrides: A New Class of Powerful, Selective,
Air-Stable Reducing Agents.
III.A-13 Cho, B.T. and Chun, Y.S., TA, 5, 1147.
72-83 %
96-99 % e.e.