Ill
REDUCTIONS
III.A. C=Q Reductions
III.A-1 Yaozhong, J. et al., TA, 5, 1211; Garcia, J. et al., TA, 5, 165;
Stone, G.B., TA, 5, 465; Williams, I.H. et al., CC, 1651; Martens, J. et al.
TA, 5, 185.
O
BH 3 , THF, rt
OH
il
PÎi
Ph
1*
R^R·
y v
R
A
R·
HN V O
60-90%
B
19-99 % e.e.
H
m.A-2 Uemura, S. et al., CC, 1375; Faller, J.W. and Chase, K.J., OM, 13,
989; Buchwald, S.L. et al., JOC, 59, 4323; Breeden, S.W. and Lawrence,
N.J., SL, 833; Halterman, R.L. et al., JOC, 59, 2642; Noyori, R. et al.,
JOC, 59, 217.
°
1: PH 2 SiH 2 , Rh(I)ligand
O H
sK n
2: HC1, MeOH
*
^K
Ar
R
Ar
R
5-100 %
lìgand = chiral diferrocenyl dichalcogenides 31-88 % e.e.
198