OXIDATIONS
179
II.B.1-9 Schulz, M. et al., SL, 669.
* " ' "
R ^ X H O
MeCN, rt
V ^ O M e
R .
2: NaOMe, MeOH
OH
rt
30-88 %
II.B.1-10 Akermark, B., Larsson, E.M., and Oslob, J.D., JOC, 59, 5729;
Ruddock, P.L. and Reese, P.B., JCR(S), 442; Shibuya, K., SC, 24, 2923.
R î - ^ ^ R
3
Pd(OAc)2
R l ^ ^ ^ R S
[
H 2 0 2 ,HOAc
[
J
R
2
benzoquinone
R
2
OAc
20-77 %
Π.Β.1-11 Hill, D.R. et al., T, 50, 2665.
The Functionalization of Saturated Hydrocarbons Part XXIX.
Application of tert-Butyl Hydroperoxide and Dioxygen Using
Soluble Fe(III) and Cu(II) Chelates.
II.B.1-12 Adam, W. et al., CB, 127, 667 and JOC, 59, 2358; Massanet,
G.M. et al, T, 50, 5439; Bovicelli, P., Mincione, E. et al., TL, 35, 935;
Jauch, J., T, 50, 12903; Curran, D.P. and Ko, S.B., JOC, 59, 6139.
0
1:LDA,THF,-78°C
0
II
2: L3T1CI
||
/ " χ ^ Μ β -^ττ:
7
J<
Me
P h ^ ^ ^
3 : Q^/
Ph
θ Α
ÔH
4: NH 4 F, H 2 0
92 %
63 % e.e.