CARBON-CARBON BOND FORMING REACTIONS
157
I.H.1-3 Saigo, K. et al., TA, 5, 1333; Fujimoto, K. and Nakai, T., TL,
35, 5019; Greeves, N. and Vines, K.J., TL, 35, 7077.
LHMDS
TMEDA, THF
-78->0°C
55-75%
(3-4.5:1)
I.H.1-4 Stevenson, P.J. et al., T, 50, 4025.
l
\X
+
Li O J L
R
R
L
R
J
R
53-92%
(0.2-11:1)
I.H.1-5 Endo, Y. et al., CPB, 42, 419.
R
J
1. LDA or KHMDS
O
THF, -78°C
2. CHN 2
*"
157
I.H.1-3 Saigo, K. et al., TA, 5, 1333; Fujimoto, K. and Nakai, T., TL,
35, 5019; Greeves, N. and Vines, K.J., TL, 35, 7077.
LHMDS
TMEDA, THF
-78->0°C
55-75%
(3-4.5:1)
I.H.1-4 Stevenson, P.J. et al., T, 50, 4025.
l
\X
+
Li O J L
R
R
L
R
J
R
53-92%
(0.2-11:1)
I.H.1-5 Endo, Y. et al., CPB, 42, 419.
R
J
1. LDA or KHMDS
O
THF, -78°C
2. CHN 2
*"