2
ORGANIC SYNTHESIS—1995
I.A.1-3 Bulman Page, P.C., TL, 35, 2607.
DUMPS ^
ρ ψ ^ - R
R =
2) DMPU
3) RI
CH,
57%
I.A.1-4 Koga, K. et al., JACS, 116, 8829.
)TMS
OTM
00
MeLi
BnBr, ligand
ligand =
LiBr, ether DME, TMEDA
Ph
Me 2 N^jC
Me
I.A.1-5 Cahiez, G. et al., TL, 35, 3065 & 3069.
i)NMnCl
fl
1) Ph(Bu)
V ^ ^ ^
2) BnBr
Pr'
79%, 92% ee
Bn
C 5
H 1 1
85%, >97% regioselectivity
ORGANIC SYNTHESIS—1995
I.A.1-3 Bulman Page, P.C., TL, 35, 2607.
DUMPS ^
ρ ψ ^ - R
R =
2) DMPU
3) RI
CH,
57%
I.A.1-4 Koga, K. et al., JACS, 116, 8829.
)TMS
OTM
00
MeLi
BnBr, ligand
ligand =
LiBr, ether DME, TMEDA
Ph
Me 2 N^jC
Me
I.A.1-5 Cahiez, G. et al., TL, 35, 3065 & 3069.
i)NMnCl
fl
1) Ph(Bu)
V ^ ^ ^
2) BnBr
Pr'
79%, 92% ee
Bn
C 5
H 1 1
85%, >97% regioselectivity